Showing posts with label medicated cycle. Show all posts
Showing posts with label medicated cycle. Show all posts

Thursday, May 15, 2008

In the End, the Odds Remained the Same

Lame.

Yesterday I went for another monitoring appointment, and the doctor determined that I just wasn't going to be ovulating this month. She said sometimes that happens with Clomid, and she said my regular doctor might want to increase the dosage. I noted that I already ovulated normally on my own, so I didn't think increasing the dosage would be useful. She said sometimes you just don't ovulate anyway. And she sent me on my way, telling me to call on my next Day 1.

I admit I wasn't looking forward to another two weeks of progesterone and the associated side effects. In fact, I was dreading it. So I'm actually kind of relieved that I don't have to go through that again this month.

But I'm done with the medicated cycles. The whole point of them was to increase the odds of a pregnancy each month by giving me meds to ensure my left ovary ovulated each time (that's the attached one). This is based on the assumption that someone with my condition starts with half the chance of a person with normal girl parts. Well, I did 4 medicated cycles. And two of them were canceled. 50%. My chances remained exactly the same.

Seriously, screw this. I'm not doing another one. I'm taking a few months off to do some crazy "Eastern medicine" herb treatments recommended by my acupuncturist. Why not? It couldn't possibly screw me up as much as the meds I've been on. It'll probably make me healthier, because the treatments include diet changes that involve copious vegetable consumption. In the fall I'll head back to the doctor if we haven't had luck on our own and if they have some new ideas.

Signed,
Your Happily Drug-Free Pal
Megan

Saturday, March 29, 2008

The Medicated Cycle

I just finished my second medicated cycle, the first one that went all the way through. Before it started I was pretty curious about how it would all go down. Everyone will have a different protocol per her doctor, but maybe this could be useful information for others to have.

Disclaimer: If you're easily grossed out, you probably want to skip this post.

On Day 3 of my cycle (the third day of bleeding), I went to the doctor for a transvaginal ultrasound (the wand that goes inside the va-jay-jay) and a blood test. The ultrasound allowed the doctor to take a look at my ovaries and ensure they didn't have any cysts left over from the last cycle. The blood test ensured I was not pregnant. I was cleared to begin medication after those tests. I started on Day 3 with 25 mg of clomiphene citate (AKA Clomid) to stimulate my ovaries. I ovulate naturally on my own, but I have a unicornuate uterus (only the left side of my uterus formed) and I have no right fallopian tube. This means that if I ovulate on the right side, the egg has no way to get to my uterus and ends up just being released into my abdomen somewhere, where it eventually dissolves. The clomid increases the chance that both ovaries will ovulate, and every time the left one works, that's a chance for pregnancy.

Clomid, however, has side effects. For me, they included increased thirst, a hot flash or two, and the most unfortunate one -- it reduced the thickness of the lining of my uterus. I took the clomid through Day 8, and starting on Day 9 I began taking a 2 mg estrogen pill called estradiol. This is a green vaginal suppository that counteracts the issue with the uterine lining. I inserted it twice a day through the remainder of the cycle. The estradiol caused intense headaches until around the time I ovulated. And because it is a green pill, it caused bright green vaginal discharge.

On Day 11, I headed in to the doctor again for another transvaginal ultrasound and blood test. At the ultrasound, I had three follicles on my right ovary (the disconnected one) and two on my left of a good size, so we were good to go. (The prior cycle had been canceled because I had no follicles on the left.) If the follicles were not large enough yet, I would have been told to come back in a day or two. This was all in preparation for my "trigger shot," which triggers ovulation.

The blood test results revealed that I had already started the 24-48 hour process of ovulation, so we were told to make sure I injected myself with my "trigger shot" that night and to ensure we did the deed that night as well.

The trigger shot is a syringe pre-filled with 250 mg of recombinant human chorionic gonadotropin. It is best injected into the belly. I was disturbed at the idea of injecting myself in my tummy, but it actually didn't hurt at all. It was trippy, sticking a needle into myself and pushing the plunger, but the pain was less than minimal.

So we did the deed that night and the next night. We were actually told to do it that night, optional for the second night, and definitely on the third morning. But I was pretty sure the show was over by the third morning, because the ovulation pains (pretty noticeable when you're on clomid) had disappeared. And the third morning was a Monday, so that was that.

I don't regret missing that last opportunity. Remember, this is a natural cycle, which means we do it the old-fashioned way, and I was inserting those little green pills. And nothing says romance like green vaginal discharge.

Starting on Day 14, I began taking prometrium capsules, which increase progesterone levels. They were also vaginal, so they got popped in right after the estradiol, creating an even greater need for a panty liner. Prometrium is supposed to help with implantation. The side effects basically mimic pregnancy, which to me is a cruel joke. My breasts were very sore, my chin broke out, and I felt irritable and tired, especially as the cycle wound down. Luckily, I'd been warned about the pregnancy symptoms, so I didn't get too excited.

At 7 a.m. on Day 28, I went in for my beta test (a blood test to check for pregnancy). I found out later that day that the test was negative.

On the bright side, I was able to stop all the meds. And the meds are not pretty. For two days after that, I still had to wear a panty liner as the meds continued to drip out. Finally, yesterday, it stopped (Day 31).

And today is a new Day 1.

Thursday, February 7, 2008

Better Luck Next Time

Today was Day 11 of my medicated cycle, so I went in to get my ovaries and lining checked. I had two great follicles -- on my right ovary. Unfortunately, since I was born without a right fallopian tube (and right side of my uterus), that is not particularly helpful. The left ovary was sitting there quietly all hooked up to my half-uterus, but keeping a low profile, follicle-wise.

The doctor said we could go ahead with the trigger shot this month on the offhand chance that -- get this -- my left fallopian tube swings over and picks up the eggs from the right ovary. (I have heard of women with unicornuate uteruses [UUs] getting pregnant when they knew the unattached ovary was the one producing eggs, so I guess that's how it goes down.) But I decided just to stop the meds for this cycle. I'd rather really go for it when the chances were high.

I'm bummed, but philosophical about the whole thing. I guess that's easy since it was the first real attempt under medical observation. I wonder how far this thing will go before we actually succeed.

Wednesday, February 6, 2008

Here Goes Nothing

Heading to my Day 3 monitoring appointment last week, I was full of angst and almost weepy. I was worried about starting the medicated cycle, afraid of the side effects, and generally dreading starting the whole process of trying to have a baby again. But I felt a lot better after coming out of the appointment. I went in there and noticed several professional women and a few husbands. Nobody was looking at each other or talking, and the women with husbands were looking extra tense. We all have a common bond, but we were sitting there in our private worlds, not sharing. The vibes passing between people are basically, "you're infertile. I'm infertile. And I don't want to talk about it." It's like a bus station full of infertile people.

After an awkward 10 minutes or so, pretending not to look at the other patients, I went back and had blood drawn. Then I was dispatched to a smaller waiting area in the back for an ultrasound, which was just to ensure my ovaries were in good shape. Another woman was sitting back there and we got to talking. She's done at least one IUI and this is her fourth IVF cycle. She went down the litany of her various tests and injections and was completely blase' about it. I felt like a big wimp.

I really hope this is her cycle.

Meanwhile, my fertility specialist suggested acupuncture, saying it seems to improve results, so I've been going and getting needles stuck into my legs and hands. I'll try to take a picture one of these times and post it on the blog. It's pretty wild. It doesn't hurt at all, though, and is actually really relaxing.

So we'll see how this goes. I'm going to try hard not to be scared, or sad, or depressed. I'm going to try to just move forward.

It's really the only thing we can do.